Tuesday, November 9, 2010
Is IPL Treatments Safe When Pregnant?
Sunday, November 7, 2010
Acne
Acne vulgaris (or acne) is a common human skin disease, characterized by areas of skin with seborrhea (scaly red skin), comedones (blackheads and whiteheads), papules (pinheads), pustules (pimples), nodules (large papules) and possibly scarring. Acne affects mostly skin with the densest population of sebaceous follicles; these areas include the face, the upper part of the chest, and the back. Severe acne is inflammatory, but acne can also manifest in noninflammatory forms. The lesions are caused by changes in pilosebaceous units, skin structures consisting of a hair follicle and its associated sebaceous gland, changes that require androgen stimulation.
Acne occurs most commonly during adolescence, and often continues into adulthood. In adolescence, acne is usually caused by an increase in male sex hormones, which people of both genders accrue during puberty. For most people, acne diminishes over time and tends to disappear — or at the very least decrease — after one reaches one's early twenties. There is, however, no way to predict how long it will take to disappear entirely, and some individuals will carry this condition well into their thirties, forties, and beyond.
Some of the large nodules were previously called "cysts" and the term nodulocystic has been used to describe severe cases of inflammatory acne. The "cysts," or boils that accompany cystic acne, can appear on the buttocks, groin, and armpit area, and anywhere else where sweat collects in hair follicles and perspiration ducts. Cystic acne affects deeper skin tissue than does common acne.
Aside from scarring, its main effects are psychological, such as reduced self-esteem[8] and, according to at least one study, depression or suicide.[9] Acne usually appears during adolescence, when people already tend to be most socially insecure[citation needed]. Early and aggressive treatment is therefore advocated by some to lessen the overall impact to individuals.
Signs and symptoms"
Typical features of acne include: seborrhea (scaly red skin), comedones (blackheads and whiteheads), papules (pinheads), pustules (pimples), nodules (large papules) and, possibly scarring. It presents somewhat differently in people with dark skin.
Scars:
Acne scars are the result of inflammation within the dermis brought on by acne. The scar is created by the wound trying to heal itself resulting in too much collagen in one spot.
Physical acne scars are often referred to as "Icepick" scars. This is because the scars tend to cause an indentation in the skin's surface. There are a range of treatments available. Although quite rare, the medical condition Atrophia Maculosa Varioliformis Cutis also results in "acne-like" depressed scars on the face.
Ice pick scars: Deep pits, that are the most common and a classic sign of acne scarring.
Box car scars: Angular scars that usually occur on the temple and cheeks, and can be either superficial or deep, these are similar to chickenpox scars.
Rolling scars: Scars that give the skin a wave-like appearance.
Hypertrophic scars: Thickened, or keloid scars.
Pigmentation:
Pigmented scars is a slightly misleading term, as it suggests a change in the skin's pigmentation and that they are true scars; however, neither is true. Pigmented scars are usually the result of nodular or cystic acne (the painful 'bumps' lying under the skin). They often leave behind an inflamed red mark. Often, the pigmentation scars can be avoided simply by avoiding aggravation of the nodule or cyst. When sufferers try to 'pop' cysts or nodules, pigmentation scarring becomes significantly worse[citation needed], and may even bruise the affected area. Pigmentation scars nearly always fade with time taking between three months to two years to do so, although rarely can persist.
Carbon Dioxide Laser (CO2 laser)
The carbon dioxide laser (CO2 laser) was one of the earliest gas lasers to be developed (invented by Kumar Patel of Bell Labs in 1964, and is still one of the most useful. Carbon dioxide lasers are the highest-power continuous wave lasers that are currently available. They are also quite efficient: the ratio of output power topump power can be as large as 20%.
The CO2 laser produces a beam of infrared light with the principal wavelength bands centering around 9.4 and 10.6 micrometers.
Amplification:
The active laser medium (laser gain/amplification medium) is a gas discharge which is air cooled (water cooled in higher power applications). The filling gas within the discharge tube consists primarily of:
Carbon dioxide (CO2) (around 10–20 %)
Nitrogen (N2) (around 10–20%)
Hydrogen (H2) and/or xenon (Xe) (a few percent; usually only used in a sealed tube.)
Helium (He) (The remainder of the gas mixture)
The specific proportions vary according to the particular laser.
The population inversion in the laser is achieved by the following sequence:
Electron impact excites vibrational motion of the nitrogen. Because nitrogen is a homonuclear molecule, it cannot lose this energy by photon emission, and its excited vibrational levels are therefore metastable and live for a long time.
Collisional energy transfer between the nitrogen and the carbon dioxide molecule causes vibrational excitation of the carbon dioxide, with sufficient efficiency to lead to the desired population inversion necessary for laser operation.
The nitrogen molecules are left in a lower excited state. Their transition to ground state takes place by collision with cold helium atoms. The resulting hot helium atoms must be cooled in order to sustain the ability to produce a population inversion in the carbon dioxide molecules. In sealed lasers, this takes place as the helium atoms strike the walls of the container. In flow-through lasers, a continuous stream of CO2 and nitrogen is excited by the plasma discharge and the hot gas mixture is exhausted from the resonator by pumps.
Contraction:
Because CO2 lasers operate in the infrared, special materials are necessary for their construction. Typically, the mirrors are silvered, while windows and lenses are made of eithergermanium or zinc selenide. For high power applications, gold mirrors and zinc selenide windows and lenses are preferred. There are also diamond windows and even lenses in use. Diamond windows are extremely expensive, but their high thermal conductivity and hardness make them useful in high-power applications and in dirty environments. Optical elements made of diamond can even be sand blasted without losing their optical properties. Historically, lenses and windows were made out of salt (either sodium chloride or potassium chloride). While the material was inexpensive, the lenses and windows degraded slowly with exposure to atmospheric moisture.
The most basic form of a CO2 laser consists of a gas discharge (with a mix close to that specified above) with a total reflector at one end, and an output coupler (usually a semi-reflective coated zinc selenide mirror) at the output end. The reflectivity of the output coupler is typically around 5-15%. The laser output may also be edge-coupled in higher power systems to reduce optical heating problems.
The CO2 laser can be constructed to have CW powers between milliwatts (mW) and hundreds of kilowatts (kW).It is also very easy to actively Q-switch a CO2 laser by means of a rotating mirror or an electro-optic switch, giving rise to Q-switched peak powers up to gigawatts (GW) of peak power.
Because the laser transitions are actually on vibration-rotation bands of a linear triatomic molecule, the rotational structure of the P and R bands can be selected by a tuning element in the laser cavity. Because transmissive materials in the infrared are rather lossy, the frequency tuning element is almost always a diffraction grating. By rotating the diffraction grating, a particular rotational line of the vibrational transition can be selected. The finest frequency selection may also be obtained through the use of an etalon. In practice, together with isotopic substitution, this means that a continuous comb of frequencies separated by around 1 cm−1 (30 GHz) can be used that extend from 880 to 1090 cm−1. Such "line-tuneable" carbon dioxide lasers are principally of interest in research applications.
Applications:
Because of the high power levels available (combined with reasonable cost for the laser), CO2 lasers are frequently used in industrial applications for cutting and welding, while lower power level lasers are used for engraving. They are also very useful in surgical procedures because water (which makes up most biological tissue) absorbs this frequency of light very well. Some examples of medical uses are laser surgery, skin resurfacing ("laser facelifts") (which essentially consist of burning the skin to promote collagen formation), anddermabrasion. Also, it could be used to treat certain skin conditions such as hirsuties papillaris genitalis by removing embarrassing or annoying bumps, podules, etc. Researchers in Israel are experimenting with using CO2 lasers to weld human tissue, as an alternative to traditional sutures.
The common plastic Poly (methyl methacrylate) (PMMA) absorbs IR light in the 2.8–25 µm wavelength band, so CO2 lasers have been used in recent years for fabricating microfluidic devices from it, with channel widths of a few hundred micrometers.
Because the atmosphere is quite transparent to infrared light, CO2 lasers are also used for military rangefinding using LIDAR techniques.